My name is Tina and I'm a data scientist and YouTuber. Bilateral trade between China and Russia in 2022 rose 34.3% year-on-year to a record high of 1.28 trillion yuan ($190 billion) in yuan-denominated terms, Chinese customs data showed in early January. My name is Tina Huang and I'm a data scientist at a FAANG company. Google Scholar. October 28 Actress #31. No need to do it alone our community of learners and instructors is there for you. Nature 555, 197203 (2018). The detailed grouping of individuals shown with empty coloured circles is described in Supplementary Data 1.I. Epoxy Flooring UAE; Floor Coating UAE; Self Leveling Floor Coating; Wood Finishes and Coating; Functional Coatings. Patterson, N., Price, A. L. & Reich, D. Population structure and eigenanalysis. Straus, L. G. The human occupation of southwestern Europe during the Last Glacial Maximum: Solutrean cultural adaptations in France and Iberia. These data suggest that the genetic ancestries identified in the pre-40ka individuals analysed so far went largely extinct or were assimilated by subsequent expansions1,9. Bioinformatics 25, 20782079 (2009). All in the name of developing an amazing product! We provide five novel insights into the genomic history of hunter-gatherer populations over a time span of 30,000 years from the Upper Palaeolithic to the Neolithic. Conversely, we reveal a genetic turnover in southern Europe suggesting a local replacement of human groups around the time of the Last Glacial Maximum, accompanied by a north-to-south dispersal of populations associated with the Epigravettian culture. Google Scholar. TV Actresses. Imbalanced aspect categorization using bidirectional encoder Jones, E. R. et al. Do you agree to our cookie policy? 5 Cliches About computer science flow chart You Should Avoid, What Freud Can Teach Us About brief candle in the dark my life in science. Its the complexity of product development, with all of its moving parts, that makes data immensely powerful. Rep. 11, 15005 (2021). The length of the colour bar shows the proportion of each ancestry. Besides, the nucleolus is involved in a variety of cellular functions including cell cycle regulation and cellular stress response. Posth, C., Yu, H., Ghalichi, A. et al. Write for us- Weird Science, Energy & Minerals Guest Post. Pleistocene North African genomes link Near Eastern and sub-Saharan African human populations. Los Angeles, California, United States. How to Rock at Data Science with Tina Huang Jon Krohn This finding, in conjunction with the genetic affinity of the Villabruna cluster to ancient and present-day Near Eastern ancestries4,15,16 (Supplementary Information, section8, Supplementary Fig. Cuando se ampla, se proporciona una lista de opciones de bsqueda para que los resultados coincidan con la seleccin actual. First up is the MIT researcher and YouTuber Jordan Harrod. As long asyouget a exam score of 60% or above,youare eligible toreceive aCourse Certificate! Now we have the founder and CEO of YSYS, Deborah Okenla. Raghavan, M. et al. First Name Tina #39. T.T., D.C. and E.A. Int. Leveraging the substantially increased sample size, we investigated genetically distinct hunter-gatherer groups for allele frequencies at selected loci that are known to be associated with specific phenotypic traits in present-day Europeans (Fig. Commun. Her YouTube channel offers tips on productivity hacks, resume evaluations, data science employment, and more. a, Population structure among Epigravettian-associated populations revealed by a neighbour-joining tree based on pairwise f2 genetic distances. Max Planck Institute for Evolutionary Anthropology. As a Graduate and Consultant in the Business Tax Advisory (Financial Services) team, I provided tax advice and tax compliance services to organisations in the banking and capital markets, wealth and . Commun. Gamble, C., Davies, W., Pettitt, P., Hazelwood, L. & Richards, M. The archaeological and genetic foundations of the European population during the Late Glacial: implications for agricultural thinking. DNA was extracted from the generated bone or tooth powder following established protocols. 2022 Weird Science Plus - All Rights Reserved. Bronk Ramsey, C. Bayesian analysis of radiocarbon dates. 771234-PALEoRIDER (to W.H. This suggests a very small recent effective population size, estimated to be in the order of around 70 individuals (Supplementary Table 2), causing the low genetic diversity in Sicilian Epigravettian hunter-gatherers. Maier, A. The sample size of individualpairsincluded in each groupis reported in SupplementaryData 3.A. Cosimo Posth, He Yu, Ayshin Ghalichi, Hlne Rougier, Isabelle Crevecoeur, Yilei Huang, Harald Ringbauer, Adam B. Rohrlach, Kathrin Ngele, Vanessa Villalba-Mouco, Rita Radzeviciute, Tiago Ferraz, Alexander Stoessel, Rezeda Tukhbatova, Dorothe G. Drucker, Martina Lari, Alessandra Modi, Stefania Vai, Tina Saupe, Christiana L. Scheib, Giulio Catalano, Luca Pagani, Sahra Talamo, Helen Fewlass, Laurent Klaric, Andr Morala, Mathieu Ru, Stphane Madelaine, Laurent Crpin, Jean-Baptiste Caverne, Emmy Bocaege, Stefano Ricci, Francesco Boschin, Priscilla Bayle, Bruno Maureille, Foni Le Brun-Ricalens, Jean-Guillaume Bordes, Gregorio Oxilia, Eugenio Bortolini, Olivier Bignon-Lau, Grgory Debout, Michel Orliac, Antoine Zazzo, Vitale Sparacello, Elisabetta Starnini, Luca Sineo, Johannes van der Plicht, Laure Pecqueur, Gildas Merceron, Graldine Garcia, Jean-Michel Leuvrey, Coralie Bay Garcia, Asier Gmez-Olivencia, Marta Potowicz-Bobak, Dariusz Bobak, Mona Le Luyer, Paul Storm, Claudia Hoffmann, Jacek Kabaciski, Tatiana Filimonova, Svetlana Shnaider, Natalia Berezina, Borja Gonzlez-Rabanal, Manuel R. Gonzlez Morales, Ana B. Marn-Arroyo, Beln Lpez, Carmen Alonso-Llamazares, Annamaria Ronchitelli, Caroline Polet, Ivan Jadin, Nicolas Cauwe, Joaquim Soler, Neus Coromina, Isaac Ruf, Richard Cottiaux, Geoffrey Clark, Lawrence G. Straus, Marie-Anne Julien, Silvia Renhart, Dorothea Talaa, Stefano Benazzi, Matteo Romandini, Luc Amkreutz, Herv Bocherens, Christoph Wiing, Sbastien Villotte, Javier Fernndez-Lpez de Pablo, Magdalena Gmez-Puche, Marco Aurelio Esquembre-Bebia, Pierre Bodu, Liesbeth Smits, Bndicte Souffi, Rimantas Jankauskas, Justina Kozakait, Christophe Cupillard, Hartmut Benthien, Kurt Wehrberger, Ralf W. Schmitz, Susanne C. Feine, Tim Schler, Corinne Thevenet, Dan Grigorescu, Friedrich Lth, Andreas Kotula, Henny Piezonka, Franz Schopper, Ji Svoboda, Sandra Szelov, Andrey Chizhevsky, Aleksandr Khokhlov, Nicholas J. Conard, Frdrique Valentin, Katerina Harvati, Patrick Semal, Bettina Jungklaus, Alexander Suvorov, Rick Schulting, Vyacheslav Moiseyev, Kristiina Mannermaa, Alexandra Buzhilova, Thomas Terberger, David Caramelli, Eveline Altena, Wolfgang Haak, Johannes Krause. The human remains were processed in dedicated laboratories at the Max Planck Institute for the Science of Human History in Jena (Germany), University of Tbingen (Germany), University of Florence (Italy), Leiden University Medical Center (the Netherlands) and University of Tartu (Estonia). A subset of samples (GER002 and GER003) were pre-treated with a washing step to reduce surface contamination54. The more information you have the more data you need to analyze and make your predictions. Genet. 40,000-year-old individual from Asia provides insight into early population structure in Eurasia. All remains were sampled with the approval of the institutions responsible for the analysis of archaeological material. Mateja Hajdinjak, Fabrizio Mafessoni, Svante Pbo, D. M. Fernandes, D. Strapagiel, R. Pinhasi, Pavel Flegontov, N. Ezgi Altnk, Stephan Schiffels, Daniel M. Fernandes, Kendra A. Sirak, David Reich, Sandra Oliveira, Kathrin Ngele, Mark Stoneking, Eirini Skourtanioti, Harald Ringbauer, Philipp W. Stockhammer, Vanessa Villalba-Mouco, Marieke S. van de Loosdrecht, Wolfgang Haak, Joseph H. Marcus, Cosimo Posth, John Novembre, Natalija Kashuba, Emrah Krdk, Anders Gtherstrm, Nature Tina Huang | Propel | Build Something Together Tina Huang. H. Rougier, I.C., L.K.,A. Morala, M. Ru, S.M., L.C., J.-B.C., E. Bocaege, S. Ricci, F.B., P. Bayle, B.M., F.L.B.-R., J.-G.B., G.O., E. Bortolini, O.B.-L., G.D., M.O., A.Z., V.S., E.S., L. Sineo, J.v.d.P., L. Pecqueur, G.M., G.G., J.-M.L., C.B.G., A.G.-O., M.P.-B., D.B., M.L.L., P. Storm, C.H., J. Kabaciski, T. Filimonova, S.Shnaider, N.B., B.G.-R., M.R.G.M., A.B.M.-A., B.L., C.A.-L., A.R., C. Polet, I.J., N. Cauwe, J.Soler, N. Coromina, I.R., R.C., G. Clark, L.G.S., M.-A.J., S. Rehart, D.T., S.B., M. Romandini, L.A., H. Bocherens, C.W., S. Villotte, J.F.-L.d.P., M.G.-P., M.A.E.-B., P. Bodu, L. Smits, B.S., R.J., J. Kozakait, C.C., H. Benthien, K.W., R.W.S., S.C.F., T. Schler, C.T., D.G., F.L., A. Kotula, H.P., F.S., J.Svoboda, S.Szelov,A.C., A. Khokhlov, N.J.C., F.V., K.H., P. Semal, B.J., A. Suvorov, R. Schulting, V.M., K.M., A.B. Maier, A. in The Central European Magdalenian 81180 https://doi.org/10.1007/978-94-017-7206-8_6 (Springer, 2015). The inferred pattern of short ROH (48 cM, visualized in blue) being common is in stark contrast to most later farmer populations, where the majority of individuals have no short ROH whatsoever (see101), and evidences small effective population sizes across West Eurasian hunter-gatherer groups. Natl Acad. PACEA co-authors of this research benefited from the scientific framework of the University of Bordeauxs IdEx Investments for the Future programme/GPR Human Past. Feb 2015 - Jun 20161 year 5 months. The dates were calibrated using OxCal 4.452 with calibration curve IntCal20 at 95.4% probability53 and when multiple dates were available for the same individual we used the function R_Combine to combine them52. You are using a browser version with limited support for CSS. Archaeological background, method descriptions and discussions additional to the main text, including sections 113, Figs. Nature 582, 384388 (2020). Tina Huang - Age, Family, Bio | Famous Birthdays In practice, we use machine learning in different conjunctures. This might also explain the genetic uniformity of the Oberkassel cluster across large parts of western Eurasia but genomic data from between 15 and 14ka is needed to understand the exact dynamics of this turnover. We use cookies to improve your experience and give you personalized content. Floor Coatings. Everything you need to know is included in the course. Content on this website is for information only. The similarity between Goyet Q116-1 and Goyet Q376-3 and the Fournol cluster is also observed at the mtDNA level, with both groups including individuals who carried mtDNA haplogroup M, which has not been found in European individuals from after the LGM24 (Extended Data Figs. b, Calibrated radiocarbon dates of individuals plotted in a. Details on the allele frequency estimates are provided in Supplementary Information, section12, Supplementary Figs. You can also check out our video on the topic below or scroll down to keep on reading. B. et al. A user manual including an installation guide is available at https://haproh.readthedocs.io/en/latest/hapROH_with_contamination.html. Living up to Expectations: The Strengths and Challenges Experienced by In addition, those groups also carry affinity to ANF suggesting more complex genetic processes behind their demographic history16. To gain an overview of the genomic background of European hunter-gatherers before the LGM, we used multidimensional scaling (MDS) to plot a dissimilarity matrix of pairwise outgroup f3-statistics in the form 1f3(Mbuti; pop1, pop2) (Fig. The compiled genotype file used for analyses, including re-genotyped published genomes, has been uploaded at the Edmond Data Repository of the Max Planck Society (https://edmond.mpdl.mpg.de/dataset.xhtml?persistentId=doi:10.17617/3.Y1KJMF). Schmitt, T. Molecular biogeography of Europe: Pleistocene cycles and postglacial trends. Evol. a, The genetic ancestry of hunter-gatherers dated between 14ka and 5.2ka modelled using qpAdm, with Oberkassel, Yuzhniy Oleniy Ostrov, Goyet Q-2 and Neolithic farmers from present-day Turkey (Barcn, Mentee and Boncuklu sites) representing Oberkassel (WHG) (blue), Sidelkino (EHG) (red), GoyetQ2 (orange) and Anatolian Neolithic farmer (green) ancestries, respectively. This study focuses on the people who lived between 35,000 and 5,000 years ago and that are, at least partially, the ancestors of the present-day population of Western Eurasia, including -- for the first time -- the genomes of people who lived during the Last Glacial Maximum (LGM), the coldest phase of the last Ice Age, around 25,000 years ago. Nature 528, 499503 (2015). EY. The number of individuals in each group is written to the right of each bar. Tina K. Sorensen | Semantic Scholar The newly generated genotypes were merged with 240 published ancient hunter-gatherer genomes and modern worldwide populations for downstream analyses (Supplementary Data 1.G). 18 and Supplementary Data 2.O), suggests the Balkans as a source of the incoming Epigravettian-associated population. By contrast, the Goyet Q116-1 genetic profile gave rise to the newly described Fournol cluster identified in Gravettian-associated individuals from western and southwestern Europe. "With these findings, we can for the first time directly support the hypothesis that during the Last Glacial Maximum people found refuge in the climatically more favourable region of southwestern Europe" says first author Cosimo Posth. Many students or recent graduates appreciate her for sharing what helped her break into the field. Internet Explorer). When expanded it provides a list of search options that will switch the search inputs to match the current selection. PubMed However, one of my favorites is using supervised learning techniques, such as random forest, SVM, and XGBoost, to discover which features contribute the most to the success of a product. The data generated in this study enabled us to investigate genomic transformations of and interactions between Eurasian hunter-gatherers at high resolution (Extended Data Fig. Tina Huang - Instructor | 365 Data Science Teaching Assistant. PubMed BMC Res. The Gravettian culture was one of the most widely distributed Upper Palaeolithic cultures across western Eurasia before the LGM19. CAS iScience 25, 104244 (2022). At this startup dedicated to b2b marketing, we, the data team formed by 2 people, are organizing all the data from zero and looking for their real value. 1a, and the y-axes report time in thousand years before present (kBP). A recent bottleneck of Y chromosome diversity coincides with a global change in culture. Nat. 4b and Supplementary Data 3.C). Fu, Q. et al. I have been watching Tina's YouTube channel's videos since the past month and find her explanations / reviews very useful and actionable and being in Toronto myself I think it will be same contextually when I start applying for DSc jobs (and make the big switch from Healthcare that I am in currently). Mathieson, I. et al. Moreover, we reveal a north-to-south decrease in genetic diversity among the Epigravettian-associated groups, with the highest PMR and heterozygosity values found in northern Italian individuals (group 1), intermediate in western and central Italian individuals (group 2) and the lowest in Sicilian individuals (group 3) (Fig. I Agree, Brandwatch Bulletin #41: 7 Women in Tech You ShouldKnow. 5). The newly reported individuals with over 15,000 SNPs on the Human Origins dataset are shown in black-outlined and filled symbols, as illustrated in the legend on the right, while representative ancient genomes are shown in outlined symbols, as illustrated in the legend at the bottom of the PCA. We then attempted to model 250 published and newly reported hunter-gatherers dated to 145ka using qpAdm as a mixture of Oberkassel, Sidelkino, GoyetQ2 ancestries, and an ancestry maximized in Anatolian Neolithic farmers (ANF), as a considerable portion of the sequenced hunter-gatherer genomes date after around 8ka, when ANF ancestry started spreading across Europe. Libraries were quantified using the IS7 and IS8 primers59 in a quantification assay using a DyNAmo SYBR Green qPCR Kit (Thermo Fisher Scientific) on the LightCycler 480 (Roche). Protoc. Low latency, reasonably low communication overhead and ability to support real time applications are the reasons for . Google Scholar. Showcase your skills and bolster your data science credentials. Protoc. Ice Age survivors. PLoS Biol. A dynastic elite in monumental Neolithic society. Ecol. This year they plan on seeing a total of 1,280 entries. Publication: Huang T, Reimand J. Network-rewiring mutation in kinase signaling networks are informative of cancer patient. Wonderful course so far Tina. Tina Huang. Dabney, J. et al. In article number 2206752, Hao Zeng and co-workers report a soft actuator assembly capable of windassisted dispersal and lift-off/landing action under the control of a light beam.The design is inspired by the seed of dandelion, resembling several biomimetic features, i.e., high porosity, lightweight, and separated vortex ring generation under a steady wind flow. and T. Saupe received support from the European Union through the European Regional Development Fund (project no. Write a sharp and effective resume in minutes and get noticed by employers. Nat. She has been working for the data sciences industry since 2014. Citing . By co-analysing previously published data with our newly reported genomes associated with the Magdalenian from La Marche (18ka) and Pincevent (15ka) in western and northern France, respectively, and Maszycka (1816ka) in southern Poland, we confirm that the Goyet Q116-1 ancestry survived in all studied Magdalenian-associated genomes besides in Gravettian and Solutrean-associated individuals from southwestern and western Europe (Fig. Tina Huang is a statistician who focuses on the statistical modeling and analysis of big data. Folding bicycle. Lipson, M. et al. Max Planck Institute for Evolutionary Anthropology. In the video above, she explains the two major components of big data: data warehousing and data science. Adv. Olalde, I. Quat. Genetically, however, the populations from western and southwestern Europe (today's France and Iberia) differed from contemporaneous populations from central and southern Europe (today's Czech Republic and Italy). Gansauge, M., Aximu-Petri, A., Nagel, S. & Meyer, M. Manual and automated preparation of single-stranded DNA libraries for the sequencing of DNA from ancient biological remains and other sources of highly degraded DNA. 2, e190 (2006). Nat. PubMed Central In this video, I had the opportunity to talk with Tina Huang, a Data Scientist at one of the FAANG companies. All Rights Reserved. K.H. 5 and Extended Data Fig. Empirically, the results show that the proposed BERT fine-tuning model with the SRS technique achieves better results. The grouping of Epigravettian-associated populations is shown with the same colour in a. Extended Data Fig. The youngest individual carrying large portions of hunter-gatherer ancestry in the analysed dataset is from Ostorf in northern Germany, dated to around 5.2ka (>90% Oberkassel clusterplus Sidelkino-clustercomponents)(Supplementary Data 3.F). I think its cool to see a project like this happen and I hope its interesting for people to learn more about how this stuff works. The Neolithic transition in the Baltic was not driven by admixture with early European farmers. Resurrected Supernova Provides Missing-Link, Bald Eagles Aren't Fledging as Many Chicks, Ultracool Dwarf Binary Stars Break Records, Deflecting Asteroids to Protect Planet Earth, Quantum Chemistry: Molecules Caught Tunneling, Shark from Jurassic Period Highly Evolved, 2.9-Million-Year-Old Butchery Site Reopens Case of Who Made First Stone Tools, Gut Microbes Can Boost the Motivation to Exercise, Warmer Climate May Drive Fungi to Be More Dangerous to Our Health, Seawater Split to Produce 'Green' Hydrogen. "Ice Age survivors." 5). 19-78-10053). Sep 2017 - Aug 20181 year. Nature 534, 200205 (2016). Archeol. This article reviews qualitative and quantitative studies related to the academic achievement of youth from immigrant Chinese families. tina huang data science Explained in Instagram Photos. We give some of our best tips to improve them and hopefully help you all land a data science interview. After the LGM, a genetic component distantly linked to the Goyet Q116-1 individual from Belgiumdated to 35 kanamed GoyetQ2 ancestry(hereafter, GoyetQ2 cluster or ancestry)reappeared in individuals from southwestern and central Europe associated with the Magdalenian culture (1914ka from Iberia to eastern Europe across central Europe) and in an admixed form in subsequent Final Palaeolithic and Mesolithic hunter-gatherers4,14, but the geographic extension of this ancestry is still unclear. PubMed Central STOC 2023: Accepted Papers Pleistocene mitochondrial genomes suggest a single major dispersal of non-Africans and a Late Glacial Population turnover in Europe. 2932 and Supplementary Table 4). The Italian peninsula was previously considered to be another climatic refugium for humans during the LGM. Originally published at https://365datascience.com on October 1, 2020. 14), most post-14ka individuals from western and central Europe fall close to the WHG cluster and those from eastern Europe close to the EHG cluster, whereas the Tutkaul 1 individual from central Asia falls close to the ANE-related group. 724703 and no. Feldman, M. et al. Second, the ancestry of individuals associated with the Epigravettian culture (Villabruna cluster), which was found to genetically connect European and Near Eastern hunter-gatherers, reached southern Europe well before the transition between the Early and Late Epigravettian4,15 and possibly as early as the GravettianEpigravettian transition. The version used for this work is archived at https://edmond.mpdl.mpg.de/dataset.xhtml?persistentId=doi:10.17617/3.Y1KJMF. The MySQL engine is also known for being extremely slow compared to others. This plot reveals the presence of three distinct groupings: (1) a pre-40ka group with individuals from the UstIshim, Bacho Kiro, Zlat k and Petera cu Oase sites, (2) a Vstonice cluster including Gravettian-associated individuals from centraleastern and southern European sites (Doln Vstonice, Pavlov, Krems-Wachtberg, Paglicci and Ostuni), and (3) a Fournol cluster(hereafter, Fournol cluster or ancestry) comprising Gravettian-associated individuals from western and southwestern European sites (Ormesson, La Rochette, Fournol and two Seriny cave sites (Mollet III and Reclau Viver)).
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