A., Cosman, F., Lakatos, P., Leung, P. C., Man, Z., Mautalen, C., Mesenbrink, P., Hu, H., Caminis, J., Tong, K., Rosario-Jansen, T., Krasnow, J., Hue, T. F., Sellmeyer, D., Eriksen, E. F., and Cummings, S. R. Once-yearly zoledronic acid for treatment of postmenopausal osteoporosis. 2006;54(10):3205-3211. Some. Osteoporos.Int. Dr. Lanis No-Nonsense Bone Health Guide. View abstract. My Dr wants me to start taking this. Low . The efficacy of glucosamine sulfate in osteoarthritis: financial and nonfinancial conflict of interest. Injecting myself daily. Gillam, D. G., Newman, H. N., Bulman, J. S., and Davies, E. H. Dentifrice abrasivity and cervical dentinal hypersensitivity. A., Johansson, H., Oden, A., and McCloskey, E. V. A meta-analysis of the effect of strontium ranelate on the risk of vertebral and non-vertebral fracture in postmenopausal osteoporosis and the interaction with FRAX((R)). View abstract. View abstract. 1992;19(10):737-740. Medi-Physics, Inc., Amersham Healthcare, Arlington Heights, IL, 1998. https://www.cancerpaintherapy.com/METATECHPAGE.htm. Roque, I. Figuls, Martinez-Zapata, M. J., Scott-Brown, M., and Alonso-Coello, P. Radioisotopes for metastatic bone pain. Fracture Intervention Trial Research Group. I have had reclast infusions for six years for osteoporosis. JAMA 8-18-1999;282(7):637-645. Skoryna SC. Rheumatol.Int. After a 7-day . If you want to take a strontium supplement, it is recommended to ask your doctor first. 2000;11(1):83-91. They won't do any studies but the END OF FRACTURES SAYS IT ALL! Eur Urol 2003;44:519-26. Strontium is a trace mineral that may aid bone health by reducing bone loss and encouraging bone development. Reginster, J., Minne, H. W., Sorensen, O. H., Hooper, M., Roux, C., Brandi, M. L., Lund, B., Ethgen, D., Pack, S., Roumagnac, I., and Eastell, R. Randomized trial of the effects of risedronate on vertebral fractures in women with established postmenopausal osteoporosis. (Accessed 13 March 2004). Cochrane.Database.Syst.Rev. View abstract. Results of a 2-year study. View abstract. J.Clin.Endocrinol.Metab 2010;95(3):1174-1181. Z. 2005;54(9):758-767. Maheu E, Mazieres B, Valat JP, et al. Some male hormones include testosterone, nandrolone, oxandrolone, and oxymetholone. Gillam, D. G., Newman, H. N., and Bulman, J. S. The effect of strontium chloride hexahydrate dentifrices on plaque accumulation and gingival inflammation. Strontium may also influence other essential functions, including calcium absorption, bone formation & breakdown, and it restores alkaline pH to improve the health of skin, hair, and nails). Bolland, M. J., Grey, A. Founded in 1999, ConsumerLab.com is a leading provider of consumer information and independent evaluations of products that affect health and nutrition. Its not an idea that is super-new either. The Alendronate Phase III Osteoporosis Treatment Study Group. If youre suffering from bone or prostate cancer, radioactive strontium therapyshould only be given by or under the direct supervision of a doctor with specialized training in nuclear medicine or radiation oncology. However, I dont advocate using these supplements without first reviewing the precautions listed below and talking with your health care provider. Perit Dial Int 1998;18:410-4. View abstract. A., Christiansen, S. C., Romundstad, P., Cannegieter, S. C., Rosendaal, F. R., and Hammerstrom, J. If you have questions on the differences between esomeprazole (Nexium) and esomeprazole strontium, or whether esomeprazole (Nexium) is an option for you, talk to your provider or pharmacist. (20). Physio Flex Pro - Editor's Choice. Fluoride helps protect your teeth from the acid that is released when this happens. Health Phys 2004;86:193-6. Clin Nucl Med 2004;29:81-5. View abstract. View abstract. Osteoporos.Int. Pearce, N. X., Addy, M., and Newcombe, R. G. Dentine hypersensitivity: a clinical trial to compare 2 strontium densensitizing toothpastes with a conventional fluoride toothpaste. A double blind, prospective, placebo-controlled study. View abstract. 2008;67(12):1736-1738. Some tetracycline antibiotics include demeclocycline (Declomycin), minocycline (Minocin), and tetracycline. 2-1-2001;344(5):333-340. Afflitto, J., Schmid, R., Esposito, A., Toddywala, R., and Gaffar, A. Fluoride availability in human saliva after dentifrice use: correlation with anticaries effects in rats. A coordinator will follow up to see if Mayo Clinic is right for you. (23), In general, taking very high doses of a Sr supplement is typically not considered safe and taking too much could even damage bones, so be careful when taking strontium, as recommended by the ATSDR (Agency for Toxic Substances and Disease Registry). View abstract. Neer, R. M., Arnaud, C. D., Zanchetta, J. R., Prince, R., Gaich, G. A., Reginster, J. Y., Hodsman, A. Basically, it is like you are consuming rocks. US Department of Health and Human Services, Public Health Service. I did find some information on the Mayo Clinic website on osteoporosis. (2). Bone mass and markers of bone and calcium metabolism in postmenopausal women treated with 1,25-dihydroxyvitamin D (Calcitrol) for four years. View abstract. J.Bone Miner.Res. The next big and interesting use of this alkaline earth metal was when it was used in the television production industry, specifically in the cathode ray tubes of color televisions. If side effects are persistent or worsen, it is best to talk to your healthcare provider. The most common supplement form is strontium citrate. J Bone Miner Res 2001;16:299-308. . View abstract. 2010;21(2):49-55. It was recommended to my sister by her doctor. Oosterhof GO, Roberts JT, de Reijke TM, et al. View abstract. The treatment can sometimes cause anemia after a few weeks, so you need to have regular blood tests after the treatment. Reginster, J. Y., Bruyere, O., Sawicki, A., Roces-Varela, A., Fardellone, P., Roberts, A., and Devogelaer, J. P. Long-term treatment of postmenopausal osteoporosis with strontium ranelate: results at 8 years. Boron seems to affect the way the . Have you discussed any treatments with your doctor or have they recommended anything to you? McClung, M. R., Geusens, P., Miller, P. D., Zippel, H., Bensen, W. G., Roux, C., Adami, S., Fogelman, I., Diamond, T., Eastell, R., Meunier, P. J., and Reginster, J. Y. Strontium ranelate may cause unwanted side effects such as stomach pain, diarrhea and headache. 1987;66(10):1518-1522. Rheumatol.Int. Arch.Intern.Med. View abstract. Osteoporos Int. This technology we use to assemble our list depends on a variety of factors, including but not limited to the following: Brand Value: Every brand of strontium citrate . (14). Eur.J.Endocrinol. View abstract. 9-1-2005;30(17 Suppl):S84-S91. (3). J.Periodontol. Boonen, S., Laan, R. F., Barton, I. P., and Watts, N. B. https://www.mayoclinic.org/diseases-conditions/osteoporosis/in-depth/osteoporosis-treatment/art-20046869. J.Clin.Endocrinol.Metab 2005;90(5):2816-2822. The drug makes your bones stronger and lowers your chances of getting fractures. Arch Intern Med 2003;163:1514-22. Results 12 weeks following cessation of 8 weeks' supervised use. Ashayeri E, Omogbehin A, Sridhar R, Shankar RA. Mason, S., Hughes, N., Sufi, F., Bannon, L., Maggio, B., North, M., and Holt, J. Eisenberg E. Effects of androgens, estrogens and corticoids on strontium kinetics in man. Gillam, D. G., Newman, H. N., Davies, E. H., and Bulman, J. S. Clinical efficacy of a low abrasive dentifrice for the relief of cervical dentinal hypersensitivity. Reginster, J. Y., Deroisy, R., Dougados, M., Jupsin, I., Colette, J., and Roux, C. Prevention of early postmenopausal bone loss by strontium ranelate: the randomized, two-year, double-masked, dose-ranging, placebo-controlled PREVOS trial. Some research says that women with osteoporosis may not absorb strontium as they should. Krachler, M., Domej, W., and Irgolic, K. J. No tummy upset this time, have been increasing very slowly as I am very med sensitive, so was on 40mg for 10 days and now 40mg one day and 80 mg every second day for a week, but the tiredness is difficult to put up with. 2006;34(8):608-613. Vertebral Efficacy with Risedronate Therapy (VERT) Study Group. View abstract. View abstract. B., Eriksen, E. F., Ish-Shalom, S., Genant, H. K., Wang, O., and Mitlak, B. H. Effect of parathyroid hormone (1-34) on fractures and bone mineral density in postmenopausal women with osteoporosis. Previous research demonstrates that strontium ranelate can promote bone formation while decreasing vertebral and nonvertebral fracture risk in women with postmenopausal osteoporosis. Brand: Algaecal. Hughes, N., Mason, S., Jeffery, P., Welton, H., Tobin, M., O'Shea, C., and Browne, M. A comparative clinical study investigating the efficacy of a test dentifrice containing 8% strontium acetate and 1040 ppm sodium fluoride versus a marketed control dentifrice containing 8% arginine, calcium carbonate, and 1450 ppm sodium monofluorophosphate in reducing dentinal hypersensitivity. Expert.Opin.Investig.Drugs 2004;13(7):857-864. In the mean time I do have bone density scans to keep an eye on bone density. (6), Strontium ranelate is a form that is sold as a prescription medication for osteoporosis and bone fractures in Europe and Australia. The effect of prior bisphosphonate therapy on the subsequent therapeutic effects of strontium ranelate over 2 years. Aging Clin.Exp.Res. View abstract. Henrotin Y, Labasse A, Zheng SX, et al. Canadian Advisory Board on Dentin Hypersensitivity. It seems to play a role in how your body makes new bone while it slows the breakdown of old bone. J.Periodontol. Strontium ranelate acts through dual mechanisms of inhibiting resorption by osteoclasts and maintaining or stimulating bone formation by osteoblasts. The compound Strontium Citrate has CAS number 40182-75- and molecular formula C6H5O7Sr-. View abstract. View abstract. You do not know the effectiveness of the supplements. [3] Bartl, R. & Bartl, C.The Osteoporosis Manual: Prevention. O'Donnell, S., Cranney, A., Wells, G. A., Adachi, J. D., and Reginster, J. Y. Strontium ranelate for preventing and treating postmenopausal osteoporosis. Increased serum strontium levels in dialysis patients: an epidemiological survey. Strontium can attach to some antibiotics called quinolones in the stomach. The radioactive form of Sr is not available as a dietary supplement, but it is considered to likely be safe when administered by a health care professional by IV. View abstract. J Biol Chem 1972;247:5520-6. Bruyre O, Reginster JY, Bellamy N, et al. Clin.Prev.Dent. View abstract. View abstract. View abstract. It is not approved in the USA.[3]. Arthritis Rheum. It seems to play a role in how your body makes new bone while it slows the breakdown of old bone. Apostolidis N, Paradellis T, Karydas A, et al. [RETRACTED]. This information may not fit your specific health circumstances. View abstract. View abstract. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version. Overview. 2008;83(5):308-314. O'Donnell S, Cranney A, Wells GA, et al. 1 Taking magnesium oxide with food can reduce stomach troubles. Erythritol: Is This Healthy Sweetener the Real Deal? After you stop taking any of these bone-building medications, you generally will need to take another osteoporosis drug to maintain the new bone growth. Boron has been consumed for menstrual cramps and boric acid has been used vaginally for yeast infections, but evidence is limited. An extensive scientific review published in 2000 concludes that: It is clear from published reports and from daily practice that injection with Sr-89 is a simple, well-tolerated treatment providing a considerable chance of good palliation of pain in patients with bone metastases from prostate cancer. (19), If youre a fan of red fireworks, you can thank strontium (specificallygaseous strontium monochloride) for that brilliant color you see every 4th of July. 1996;67(8):737-742. The typical diet includes 0.5 to 1.5 milligrams of strontium each day. Bruyere, O., Roux, C., Detilleux, J., Slosman, D. O., Spector, T. D., Fardellone, P., Brixen, K., Devogelaer, J. P., Diaz-Curiel, M., Albanese, C., Kaufman, J. M., Pors-Nielsen, S., and Reginster, J. Y. A typical dosage of strontium in over-the-counter supplements is 680 mg a day. Adami, S. Protelos: nonvertebral and hip antifracture efficacy in postmenopausal osteoporosis. Its also referred to as being a soft metal like lead. It is given as an injection every month at your doctor's office and is limited to one year of treatment. A. Seeman, E., Vellas, B., Benhamou, C., Aquino, J. P., Semler, J., Kaufman, J. M., Hoszowski, K., Varela, A. R., Fiore, C., Brixen, K., Reginster, J. Y., and Boonen, S. Strontium ranelate reduces the risk of vertebral and nonvertebral fractures in women eighty years of age and older. J.Bone Miner.Res. Arthritis Rheum 1998;41:81-91. Incidence and mortality of venous thrombosis: a population-based study. Unfortunately, a lot of toothpastes that contain Sr may contain a lot of other questionable ingredients, so I recommend sticking with a natural toothpaste or making your own at home such as myHomemade Probiotic Toothpaste. View abstract. Mazor, Z., Brayer, L., Friedman, M., and Steinberg, D. Topical varnish containing strontium in a sustained-release device as treatment for dentin hypersensitivity. 4-12-2005;172(8):1039-1043. The drug name for this radioactive form is Metastron. Strontium ranelate: dose-dependent effects in established postmenopausal vertebral osteoporosis--a 2-year randomized placebo controlled trial. Most calcium supplements are big and difficult to swallow. 2017 Aug;55(8):93-94. ", Beth Israel Deaconess Medical Center: "Strontium. In the human body, approximately 99 percent of Sr is located in the bones. View abstract. Lyles, K. W., Colon-Emeric, C. S., Magaziner, J. S., Adachi, J. D., Pieper, C. F., Mautalen, C., Hyldstrup, L., Recknor, C., Nordsletten, L., Moore, K. A., Lavecchia, C., Zhang, J., Mesenbrink, P., Hodgson, P. K., Abrams, K., Orloff, J. J., Horowitz, Z., Eriksen, E. F., and Boonen, S. Zoledronic Acid in Reducing Clinical Fracture and Mortality after Hip Fracture. Boron is an element. Before you consider calcium supplements, be sure you understand how much calcium you need, the pros and cons of calcium supplements, and which type of supplement to choose. Although Sr-89 is mostly used when there are several painful metastatic sites, its application in earlier stages of the disease is beneficial, and it may decrease progression and the need for external radiotherapy. View abstract. Int.J.Rad.Appl.Instrum.B 1987;14(3):219-222. Osteoporosis Int. 2008;23(3):433-438. J Rheumatol 2000;27:205-11. 2013 Feb;72(2):179-86. doi: 10.1136/annrheumdis-2012-202231. 2008;9:165. It is said to have first been found in the ores of lead mines in Strontian in 1787. American Bone Health4208 Six Forks RoadSuite 1000Raleigh, NC 27609. Strontium controls the activity of OPG and RANKL; these are essential molecules that regulate the rates of bone resorption. Rheumatology (Oxford). A special form of strontium called strontium ranelate can increase bone formation and prevent bone loss when used in postmenopausal women with osteoporosis. Cottage cheese, 1% milk fat, 1 cup 138 mg per serving. 1980;51(10):578-581. Do not take it within 2 hours of ingesting calcium so I take it at bedtime. Male hormones (Androgens) might decrease how fast the body gets rid of strontium. The Earths crust also has Sr at an estimated average of 360 parts per million. Causes, symptoms, risk factors, and treatment. Gunawardana DH, Lichtenstein M, Better N, Rosenthal M. Results of strontium-89 therapy in patients with prostate cancer resistant to chemotherapy. View abstract. My teeth are really strong and it feels like my bones are too. View abstract. B., Gamble, G. D., and Reid, I. R. Effect of osteoporosis treatment on mortality: a meta-analysis. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you. View abstract. Incorporation and distribution of strontium in bone. J Can Dent Assoc 2003;69:221-6. How can Sr be used? Reginster JY, Badurski J, Bellamy N, Bensen W, Chapurlat R, Chevalier X, Christiansen C, Genant H, Navarro F, Nasonov E, Sambrook PN, Spector TD, Cooper C. Efficacy and safety of strontium ranelate in the treatment of knee osteoarthritis: results of a double-blind, randomised placebo-controlled trial. I was told by the endocrinologist who I went to for osteoporosis that AlgaeCal is no better than taking calcium and vitamin D. I am reading the book "Strong Women, Strong Bones" and I highly recommend it. 2002;17(3):449-454. Calcif Tissue Int 2000;67:122-7. View abstract. Relationship between bone mineral density changes and fracture risk reduction in patients treated with strontium ranelate. A prescription form of strontiumstrontium ranelate (the ranelate salt), known as Protelos/Osseor was authorized in the European Union to treat severe osteoporosis in women who have been through the menopause and men who are at high risk of broken bones or fracture in the spine and the hip. View abstract. 1967;5(6):318-321. 2005 - 2023 WebMD LLC. Ardissino G, Schmitt CP, Bianchi ML, et al. Human biokinetics of strontium--part II: Final data evaluation of intestinal absorption and urinary excretion of strontium in human subjects after stable tracer administration. Disease-modifying effect of strontium ranelate in a subset of patients from the Phase III knee osteoarthritis study SEKOIA using quantitative MRI: reduction in bone marrow lesions protects against cartilage loss. The objective of this study was to determine whether strontium citrate can be used to enhance bone healing during MDO in a rabbit model.